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Prof. Xinyuan Zhu (PI)

职位:工学博士,教授

研究方向:1、高度支化聚合物的可控制备及功能化 2、生物医用高分子材料


Prof. Zhu Xinyuan, Ph.D (Principal Investigator)
President, University of Shanghai for Science and Technology

Professor, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University


Research Focus
Focusing on studies of polymer materials and nano-biomedicine. As leading scientist and principal investigator, Prof. Zhu is funded by national, provincial and ministerial projects, and collaborations with industries. Some research and technologies were transferred in industrial applications.


Contact Information
Office Phone: +86-21-34203400
Email: xyzhu@sjtu.edu.cn
Mailing Address: 3rd floor, Chemistry Building C annex buliding, 800 Dongchuan Road, Shanghai, China



Education

  • 1990-1994: Bachelor’s Degree, College of Materials Science and Engineering, Donghua University

  • 1994-1997: Master’s Degree, College of Materials Science and Engineering, Donghua University

  • 1998-2001: Ph.D., School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University


Professional Experience

  • 1997-1999: Teaching Assistant, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University

  • 1999-2000: Lecturer, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University

  • 2000-2005: Associate Professor, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University

  • 2003-2005: Postdoctoral Researcher, Institute of Supramolecular Science and Engineering, University of Strasbourg, France

  • 2005-Present: Professor, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University

  • 2005-2013: Deputy Director, Analysis and Testing Center, Shanghai Jiao Tong University

  • 2006-Present: Doctoral Supervisor, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University

  • 2008-Present: Deputy Director, State Key Laboratory of Metal Matrix Composites

  • 2013-2015: Vice Dean, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University

  • 2015-2017: Party Chief, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University

  • 2017-2018: Dean and Deputy Party Chief, School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University

  • 2018-2020: Executive Deputy Director, Institute of Science and Technology Development, Shanghai Jiao Tong University

  • 2020-Present: Director, Institute of Science and Technology Development, Shanghai Jiao Tong University

  • 2021-2024: Member of the Standing Committee of the Party Committee and Vice President, Shanghai Jiao Tong University

  • 2024-present: President, University of Shanghai for Science and Technology


Research Areas

  1. Controlled synthesis and functionalization of hyperbranched polymers

  2. Biomedical polymer materials


Research Projects
Multiple research projects including those under the "Chang Jiang Scholars Program," National Science Fund for Distinguished Young Scholars, National Natural Science Foundation of China, New Century Excellent Talents Program, Shanghai Rising Star Program, Shanghai Rising Star (Tracking), Shanghai Dawn Program, Fok Ying-Tong Education Foundation, among others.


Selected Publications

Papers

  1. R Dong, Y Zhou, X Zhu. Supramolecular dendritic polymers: from synthesis to applications, Accounts of Chemical Research 2014, 47 (7), 2006-2016.

  2. D Wang, T Zhao, X Zhu, D Yan, W Wang. Bioapplications of hyperbranched polymers, Chemical Society Reviews, 2015, 44 (12), 4023-4071.

  3. H Jin, W Huang, X Zhu, Y Zhou, D Yan. Biocompatible or biodegradable hyperbranched polymers: from self-assembly to cytomimetic applications, Chemical Society Reviews, 2012, 41 (18), 5986-5997.

  4. D Wang, Y Jin, X Zhu, D Yan. Synthesis and applications of stimuli-responsive hyperbranched polymers, Progress in Polymer Science, 2017, 64, 114-153.

  5. Y Zhou, W Huang, J Liu, X Zhu, D Yan. Self‐assembly of hyperbranched polymers and its biomedical applications, Advanced Materials, 2010, 22 (41), 4567-4590.

  6. Q Zheng, B Zhou, J Bai, et al. Self‐organized TiO2 nanotube array sensor for the determination of chemical oxygen demand, Advanced Materials, 2008, 20 (5), 1044-1049.

  7. R Dong, Y Zhou, X Huang, et al. Functional supramolecular polymers for biomedical applications, Advanced Materials, 2015, 27 (3), 498-526.

  8. D Wang, C Yu, L Xu, et al. Nucleoside analogue-based supramolecular nanodrugs driven by molecular recognition for synergistic cancer therapy, Journal of the American Chemical Society, 2018, 140 (28), 8797-8806.

  9. D Wang, B Liu, Y Ma, et al. A molecular recognition approach to synthesize nucleoside analogue-based multifunctional nanoparticles for targeted cancer therapy, Journal of the American Chemical Society, 2017, 139 (40), 14021-14024.

  10. Z Jia, H Chen, X Zhu, et al. Backbone-thermoresponsive hyperbranched polyethers, Journal of the American Chemical Society, 2006, 128 (25), 8144-8145.

  11. P Huang, D Wang, Y Su, et al. Combination of small molecule prodrug and nanodrug delivery: amphiphilic drug–drug conjugate for cancer therapy, Journal of the American Chemical Society, 2014, 136 (33), 11748-11756.

  12. R Dong, B Zhu, Y Zhou, et al. "Breathing" vesicles with jellyfish‐like on–off switchable fluorescence behavior, Angewandte Chemie International Edition, 2012, 51 (46), 11633-11637.

  13. L Chen, X Zhu, D Yan, et al. Controlling polymer architecture through host–guest interactions, Angewandte Chemie International Edition, 2006, 45 (1), 87-90.

  14. Q Mou, Y Ma, G Pan, et al. DNA Trojan horses: Self‐assembled floxuridine‐containing DNA polyhedra for cancer therapy, Angewandte Chemie, 2017, 129 (41), 12702-12706.

Books

  1. Hyperbranched Polymers: Synthesis, Properties, and Applications, Wiley-VCH, Chapter 11, Chapter 12, 2011.

  2. Functional Polymers for Nanomedicine, RSC, Chapter 5, 2013.


Academic Roles

  • Associate Editor of Colloids and Surfaces B: Biointerfaces

  • Editorial Board Member of Biomacromolecules, Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, Functional Composite Materials, and Chinese Journal of Polymer Science

  • International expert reviewer for the characterization of single-wall carbon nanotubes

  • Review expert for the Chemistry Division of the National Natural Science Foundation of China


Awards and Honors

  • 2006: Shanghai Rising Star

  • 2006: New Century Excellent Talents Program, Ministry of Education

  • 2007: First Prize of Shanghai Natural Science Award

  • 2008: Shanghai Dawn Scholar

  • 2008: 11th Fok Ying-Tong Foundation Award

  • 2009: Second Prize of National Natural Science Award

  • 2010: National Science Fund for Distinguished Young Scholars

  • 2011: Shanghai Rising Star (Tracking)


Teaching

  1. Undergraduate: Nanobiomaterials

  2. Undergraduate: Biomedical Materials


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